Abstract
A great many disorders including
maturity-onset (type II) diabetes, hypertension, and
hypertriglyceridemia are frequently
associated with adult-onset obesity and improve
with caloric restriction. It is the premise of this brief review that
there
are patients with these disorders who are not obese
according to standard weight tables or other readily-available
criteria;
but who would also respond favorably to caloric
restriction. It is proposed that such individuals might be characterized
by
hyperinsulinism and possibly an increase in fat
cell size compared to patients of similar age, height, and weight and/or
to
themselves at an earlier time. The possibility is
also discussed that inactivity is a contributing factor in some of these
individuals and that for them, the appropriate
therapy might be exercise.
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